Imipramine (hydrochloride) serotonin and norepinephrine transporters inhibitor Recommended primary dilution is 1/10,000 1/15,000 in PBS/0.3 Triton X-100 Biotin/avidin-HRP. The serotonin transporter (SERT) regulates neurotransmitter homeostasis through the sodium- and chloride-dependent recycling of serotonin into presynaptic neurons 1, 2, 3. The antiserum demonstrates strongly positive labeling of rat raphe nuclei, hypothalamus, cortex and spinal cord using indirect immunofluorescent and biotin/avidin-HRP techniques.
Mice with deletion of SERT develop metabolic syndrome as they age. Amitifadine hydrochloride (DOV-21947 hydrochloride)Ĭentanafadine hydrochloride (EB-1020 (hydrochloride))Ĭitalopram hydrobromide 5-HT uptake inhibitorĬlomipramine HCl SERT/NET dopamine transporter (DAT) blockerĭapoxetine HCl Selective serotonin reuptake inhibitorĭasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.ĭasotraline hydrochloride Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.ĭesipramine hydrochloride noradrenalin transporters inhibitorĭesvenlafaxine serotonin (5-HT) and norepinephrine (NE) reuptake inhibitorĭesvenlafaxine Succinate serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitorĮscitalopram Serotonin reuptake inhibitorĮscitalopram Oxalate Selective 5-HT reuptake inhibitorįluoxetine (LY-110140) A selective serotonin reuptake inhibitor for antidepressant researchįluoxetine HCl Serotonin reuptake inhibitor,selectiveįluvoxamine Selective serotonin reuptake inhibitorįluvoxamine maleate Serotonin reuptake inhibitor,selective,antidepressant The ImmunoStar serotonin (5HT) transporter was quality control tested using standard immunohistochemical methods. Serotonin transporter (SERT) plays a critical role in regulating extracellular availability of serotonin (5-HT) in the gut and brain.
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